HYPOCALORIC DIET IN PERINATAL LIFE FOLLOWED BY OBESITY EXACERBATES METABOLIC DISORDERS IN THE OFFSPRING OF WISTAR RATS

Hypocaloric diet in perinatal life followed by obesity exacerbates metabolic disorders in the offspring of wistar rats

The effects of an obesogenic post-weaning diet on the growth and metabolic parameters of adult offspring submitted to a hypocaloric diet in perinatal life were evaluated.Male Wistar rats were divided into two groups according to maternal diet Rolling Pins during pregnancy and lactation: Control (C, received normocaloric diet) and hypocaloric diet d

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The Selective Rat Toxicant Norbormide Blocks KATP Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells

Norbormide is a toxicant selective for rats to which it induces a widespread vasoconstriction.In a recent paper, we hypothesized a role of ATP-sensitive potassium (KATP) channels in norbormide-induced vasoconstriction.The current study was undertaken to verify this hypothesis by comparing the effects of norbormide with those of glibenclamide, a kno

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